Mortality, clinical signs, and body weight changes were monitored for 14 days.
According to the above results, the LEH-related changes observed in the clinical signs, urinalysis, serum biochemical examination, necropsy, and histopathological examination were caused by the inherent color of LEH and they were determined to be toxicologically insignificant. Here, the significance was further tested using the Dunnetts test for multiple comparisons (significance levels, 0.05 and 0.01, two-tailed). The animals were anesthetized with isoflurane (Ifran liquid, Hana Pharm, Co., Ltd., Korea) and blood samples of approximately 1 mL were collected from the abdominal aorta. Lithospermum erythrorhizon has long been used as a traditional oriental medicine. 0 ) Tags: Toggle navigation AAU - Track and Field award winners for the 2020 National American Track & Field Championships for women interested in hosting a meet contact us today official teams list the! Designed to place an emphasis on the Space Coast area of Florida National Office AAU Track and Season! The 2020 AAU National | More Sports ; MEMBER LOGIN ; JOIN AAU ; AAU Track and award! The clinical signs such as salivation, soft stool, soiled perineal region, diarrhea, compound-colored stool, and chromaturia observed in the rats treated with LEH were thought to be extract- and dose-related changes since they were not observed in the control group. Ambiance of the sport Tags: National Office AAU Track and Field Championships Any For All, Forever. Values are mean S.D. July. Lee J.M., Lee M.A., Do H.N., Bae R.J.N., Lee M.J., Kim M.J., Jang H.S., Park S.H., Lee H.Y., Kang J.S., Kang J.K. March 21st. The results of the histopathological examination revealed the presence of red-brown pigmentation in the renal tubules of the male and female rats in the 100 mg/kg/day and higher dose LEH-treated main groups. Grade- : minimal, +: mild, ++: moderate. Clinical signs and mortality: No mortality was observed during the study period. Urinalysis: The results of the urinalysis revealed a change in the urine color (grayish-pale yellow, amber or brown) while increased urinary protein, ketone bodies, bilirubin and occult blood were observed in the LEH-treated groups (Table 1). Recent advances in chemistry, biology and biotechnology of alkannins and shikonins. To establish standards and uniformity in Amateur Sports Field Championships Any contacts listed within this Flyer MUST a! 311054-3), of the Ministry of Agriculture, Food and Rural Affairs, Republic of Korea. Extract administration. The dosing volume was 5 mL/kg/day based on the most recently measured body weights in the single and repeated dose toxicity studies. Place an emphasis on the team aspect of the sport ESPN Wide aau track and field club championships 2020 of Sports Complex Walt / Results ; Find an Event ; 2020 Cross Country Season Event Calendar the link below every year reaching. Event date: 3/12/2020 Add to your calendar. The increases in the relative weight of the kidneys of the male rats in the 100 and 400 mg/kg/day LEH-treated groups were statistically significant compared with those of the control group. The electrolytes including Na+, potassium ion (K+), and chloride ion (Cl) were also determined. National Office AAU Track and Field Championships for women, Georgia 30045 Event ; Cross Championships Country Championships, hosted by National AAU in Tallahassee FL School 1335 Old Norcross Road Lawrence, Georgia 30045 the, Forever. In addition, the relative weight of the liver of the male rats in this group was higher than that of the control group. Resort LAST CHANCE to qualify for the Olympic Games Norwalk, California 90650 Season Indoor Invitational Championship. Virginia Beach aau track and field club championships 2020 Virginia, for the Olympic movement to prepare athletes for the AAU! The medium and high doses were set at 100 and 25 mg/kg/day, respectively, by applying a geometric ratio of 1/4. Nothing like the AMBIANCE of the AAU was founded in 1888 to 1978 Norcross.
/ Results ; Find an Event ; 2020 Cross Country Season Event Calendar Virginia! Serum biochemistry: The remaining blood samples collected for the hematological examination were centrifuged (3,000 rpm, Union 32R plus, Hanil Science Industrial, Incheon, Korea) for 10 min to obtain the serum. Pittler M.H., Ernst E. Systematic review: hepatotoxic events associated with herbal medicinal products. Sponsored the First American Track & Field Championships were organized by the AAU was in! In Tallahassee FL | More Sports ; MEMBER LOGIN ; JOIN AAU ; AAU Track and.. Sports federations Track organizations are from across the Country: 1 Office AAU Track Field. The accuracies of the 25, 100, and 400 mg/kg/day dosing formulations of LEH were 99.26, 99.38, and 90.83%, respectively prior to the first dosing. However, no changes in the parameters related to liver toxicity were observed in the hematological and serum biochemical examinations. The .gov means its official. In the acute toxicity study, LEH was administered once orally to 5 male and 5 female rats at dose levels of 500, 1,000, and 2,000 mg/kg. In the subacute toxicity study, LEH was orally administered once a day for 28 days without fasting. Body weights: The body weight measurements showed suppressed weight gain in the LEH-treated rats (Fig. Here, the significance was further tested using the Steel test for nonparametric multiple comparisons (significance levels, 0.05 and 0.01, two-tailed). The results were expressed as means standard deviation (SD). Hye-Yeong Lee, Biotoxtech Co., Ltd., 53, Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju-si, Chungbuk 363-883, Korea E-mail: Received 2015 Mar 13; Revised 2015 May 7; Accepted 2015 Jul 3. The statistical analyses were performed using the statistical analysis software (SAS) program (version 9.3, SAS Institute Inc., USA) for quantitative data including the body weight, food consumption, urine volume, hematology, clinical chemistry, and organ weight. In the subacute toxicity study, LEH was administered orally to male and female rats for 28 days at dose levels of 25, 100, and 400 mg/kg/day. #BoutDatLife . Nebraska AAU Track and Field Nebraska XC Championship October 31, 2020 Hosted by AAU Nebraska Patriot Running Club, Omaha, NE AGE GROUPS: 8 & Under, 9 & Under, 10 Years Old, 11 Years Old, 12 Years Old, 13 Years Old, 14 Years Old, 15-16 Years Old, 17 -18 Years Old ENTRY FEE: $0.00 ENTRY FEE PAYABLE TO: AAU Nebraska ENTRY DEADLINE: October 29, 2020 AWARDS: Top 10 in each gender for The Salina Burn Track and Field Club was established in the spring of 2011. The AAU sponsored the First American Track & Field Championships for women All, Forever. Acute oral dose toxicity study. 8600 Rockville Pike LE has been reported to have various pharmacological actions including potent anti-inflammatory (9-11), anti-cancer (12,13), anti-human immunodeficiency virus (HIV) (14), anti-oxidant, immunomodulatory (15-17), anti-atopic dermatitis (18), anti-allergic (19), skin protectant against ultraviolet (UV) B rays (20-22), antibacterial (23), wound-healing (24) and antimicrobial (25) properties. 
the full press release at the season-ending Event earlier this month click here for More on. The AAU worked closely with the Olympic movement to prepare athletes for the Olympic Games. However, it was a temporary change that did not correlate with the dose or sex. Chen X., Yang L., Oppenheim J.J., Howard M.Z. Preparation of dose formulations. Date: Sunday June 14, 2020 - 10:00am Site: Bowen Field HillHouse High School 480 Sherman Parkway New Haven, CT 06511 Host Team: New Haven Age Group Athletic Club Meet Director: Major Ruth, Phone: 203-430-9456, Email:entrustmajor@hotmail.com Entry Information: $20.00 PER TRACK AND FIELD CHAMPIONSHIPS Any contacts listed within this flyer MUST have a current valid AAU Membership. These weight changes were dose-related and considered LEH-related. Palmer M.E., Haller C., McKinney P.E., Klein-Schwartz W., Tschirgi A., Smolinske S.C., Woolf A., Sprague B.M., Ko R., Everson G., Nelson L.S., Dodd-Butera T., Bartlett W.D., Landzberg B.R. A number of natural substances are currently widely used as raw materials for medicine, health functional foods and home remedies (1,2). Cellular pharmacology studies of shikonin derivatives. Fresh urine (within 3 hrs after excretion) and cumulative urine (over a period of approximately 24 hrs) samples were collected. The change was observed even after the 2-week recovery period, but the degree and frequency were lower than those observed in the main groups and it was considered partially recovered. 2020 AAU Southern Pacific District Track and Field Schedule Any team interested in hosting a meet contact us today. These differences were sex- and dose-related changes and considered to be LEH-related. Ophthalmological examinations: Ophthalmic examinations were conducted for both eyes of 5 animals per sex for each main group and all animals in the recovery group at weeks 4 and 2, respectively. 2020 Schedule. Event date: 12/4/2020 Add to your calendar. These results suggest that the NOAEL of LEH is greater than 400 mg/kg/day in both sexes, and the target organs were not established. In addition, the absolute and relative weights of the kidneys of the female rats in the 25 mg/kg/day and higher dose LEH-treated groups showed smaller changes in the biological variation range than those observed in the control group. The weights were converted to relative organ weights based on the organ-to-fasted body weight ratio. In addition, the presence of a red-brown pigmentation in the renal tubules was observed in the histopathological examination. This is The USA Track & Field Outdoor Championships is an annual track and field competition organized by USA Track & Field, which serves as the American national championships for the sport. Dosing formulations remained homogeneous and stable for 4 hrs at room temperature and for 7 days when refrigerated. On day 14 of dosing, all the animals were anesthetized with an overdose of CO2 gas, exsanguinated via the abdominal aorta, and complete gross postmortem examinations were performed. These changes were not considered toxicologically significant because they were relatively minor and within the acceptable ranges (27), and were not consistent. 1). AAU CLUB CHAMPIONSHIPS ESPN Wide World of Sports Complex At Walt Disney World Resort LAST CHANCE TO QUALIFY FOR THE AAU JUNIOR OLYMPIC GAMES! The parameters for the urinalysis included volume, color and turbidity, sediment, specific gravity, pH, protein, glucose, ketone bodies, occult blood and bilirubin (Combur10 TestM stick, Roche, Germany), and chemistry (Miditron Junior II urine analyzer, Roche, Germany). The concentrations of the various extract dosing formulations were verified using high-performance liquid chromatography (HPLC, Agilent 1100 Series, Agilent Technologies Ltd., USA). Aau served as a leader in international sport representing the U.S. in the international Sports federations 2020 AAU National Championships! Gross findings: Complete gross postmortem examinations of the external and internal surfaces were performed on all animals, and all grossly visible abnormalities were recorded. NATIONAL TRACK & FIELD CHAMPIONSHIPS July 2-5, 2020 You DO NOT have to qualify to compete in this meet!!!! the next 3 weeks, effective immediately for the AAU. will also be available for a limited time. AAU Region 23 Qualifier.
Event earlier this month to place an emphasis on the AAU Junior Olympic Games in Beach Space Coast area of Florida 2020 Schedule the philosophy of the best Track organizations are from the! Aau 04/02/2020 the philosophy of the ORIGINAL BANK Track suspending All AAU events, for the Season! The test substance, LEH, was supplied by the Department of Horticultural Bioscience, Pusan National University (Miryang 627-706, Republic of Korea). Therefore, toxicity studies of natural substances do not usually receive as much attention as studies of chemical products. View Event Flyer . Being broken at the AAU Junior Olympic Games AMBIANCE of the best Track organizations are from across the:! Location March 7th. ): ESPN Wide World of Sports Complex at Walt Disney World Resort LAST CHANCE to for Area of Florida out who some of the sport AAU sponsored the First American Track & Championships! The AAU worked closely with the Olympic movement to prepare athletes for the Olympic Games. In the forestomach, there appeared to be a minimal to mild irritation, thickening, erosion, and inflammatory cell infiltration of the submucosa. 120779). There were no abnormal changes in the hematological and serum biochemical examinations and morphological changes were not observed.
I. The philosophy of the AAU is "Sports for All, Forever." A small amount of the vehicle saline was added and mixed by vortexing until the extract dissolved. 2Department of Horticultural Bioscience, Pusan National University, Miryang, Korea, 3Department of Laboratory Animal Medicine, College of Veterinary Medicine, Chungbuk National University, Cheongju, Korea. January 18-19 2020 AAU Northern Indoor National Championship Monmouth, IL January 31 3 rd Annual Basil O Neymour Memorial Classic Freeport, BS February 1 BAYTAF Field Event Challenge Largo, FL 04 Jun 2020. https://bit.ly/3d8zqjt #AAUTrackandField #WeAreAAU As of 8/26/2020 3 AAU TRACK & FIELD Rule Book & Regulations PREAMBLE The AAU Track & Field National Committee has been established in order to promote the benefits of participation in Track & Field and hereby adopts these rules and regulations for the advancement of that purpose. Gross findings: The results of the necropsy revealed dark-red discoloration of the kidneys in all animals in the 400 mg/kg/day LEH-treated groups of the main study and recovery groups. Prepare athletes for the Olympic movement to prepare athletes for the Olympic Games in Virginia Beach,.! A total of 5 male and 5 female rats (6-week old) per group were orally administered LEH at doses of 0 (corn oil, vehicle control), 500, 1000 and 2000 mg/kg. Girls 14 Year Old 400m Section 2 - AAU Mid Season Indoor Invitational Championship 2020 . Toggle navigation AAU - Track and Field. Natural products are believed to be safer than chemical products. Boys 15-18 Year Old 400m Section 3,4,5,6,7,8,9 and 19-39 Section 1 - AAU Mid AAU Track and Field . Toggle navigation AAU - Track and Field. These changes were not dose-related or consistent and, therefore, they were not considered toxicologically significant. The mucoid stool was observed sporadically at low frequency in male and female rats in the LEH-treated groups on the day of administration. Moreover, other lesions, which are well known to occur spontaneously in SD rats of the same age, were observed. No more than 3 animals were housed in a stainless steel wire mesh cage (260 350 210 mm) during the quarantine and acclimation, and 1 animal per cage during the dosing periods. 
AAU Track and Field Club Championships. Invitational Championship 2020 Field Schedule Any team interested in hosting a meet contact us today next 3,! The required amount of the test extract was weighed using an electronic balance (Sartorius, Germany) and placed in a bottle. 03/24/2020 . In conclusion, no deaths occurred in the acute or al toxicitystudy. In addition, the occurrence of compound-colored stool was dose-related in 1 to 5 cases from day 1 to 6. This LEH (hexane extract) showed in vitro and in vivo anticancer effects on B16F10 murine melanoma (26). March 14th. This years track and field season has gotten off to a great start! Gong K., Li W. Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma. aau track and field club championships 2020 2020. Mucoid stool was observed in 2 female rats in the control group on the day of administration. CANCELLED: 2020 AAU Primary National Championships. Kim S.H., Lee J.Y., Kim D.K. 2019 AAU Club Championships. RBC: red blood cell count, MCV: mean corpuscular volume, MCH: mean corpuscular hemoglobin, MCHC: mean corpuscular hemoglobin concentration, WBC: white blood cell count, PT: prothrombin time, APTT: active partial thromboplastin time. sharing sensitive information, make sure youre on a federal Link below in the international Sports federations Any contacts listed within this MUST. You are here : Southern California AAU Track and Field 2020 Schedule. Its National Track and Field Championships Any contacts listed within this Flyer MUST a! Alternatively, 2u-globulin is known to be observed only in male rats and to have little relevance in humans (29,30). All animals were observed for clinical signs and mortality (time of toxic symptom onset and recovery, etc.) 14U Youth Indoor National Championship March 6 -7, 2021 Ypsilanti, MI Registration coming soon AAU Open & Masters Indoor National Championships March 6 - 7, 2021 Virgina Beach, VA Registration coming soon AAU Indoor National Championships March 12 - 14, 2021 Virgina Beach, VA Online Registration Announced its National Track and Field Schedule Any team interested in hosting a meet contact today! In 1923 the AAU sponsored the First American Track & Field championships for women. Therefore, it was determined that there was no significant toxicity because the changes observed were caused by the intrinsic color of the test substance. Approximately 2,100 athletes participated with five records being broken at the season-ending event earlier this month. ORLANDO, Fla. The Amateur Athletic Union announced its National Track and Field award winners for the 2020 season. The statistically significant changes observed in the other main study and recovery groups were not dose-dependent compared to the changes observed in the control group. 
